Pernaton Green Lipped Mussel Gel for Joint Care, Natural Cooling Gel for Joint Pain, Arthritis, Sciatica, Pain Relief Gel for Joints and Muscles with Original Perna Extract, 125ml

Product Information

Limited clinical studies suggest that Perna mussel extracts may have efficacy in the treatment of diseases with inflammatory components, such as arthritis and asthma. However, conflicting trial results have been reported. Dosing

The degree of hydrolysis was measured using OPA (O-phthalaldehyde) according to the method of Nielsen et al. [ 13]. Spectrophotometric analysis was carried out with the help of an Enspire multimode reader (Perkin Elmer Inc., Waltham, MA, USA) at 340 nm. Samples of 100 mg of freeze-dried pepsin or alcalase hydrolysates were weighed into volumetric flasks and made up to 10 mL with MilliQ water to obtain a 10 mg/mL concentration. To confirm the legitimacy of the product, is it advised to look for a GMP label and verification of ingredients list to ensure safety.Green-lipped mussels ( Perna canaliculus) only grow in the unique marine conditions found around New Zealand. The beautiful green-lipped mussel is prized for its plump, juicy flesh and attractive shells, but interest in their health benefits and medicinal properties arose when researchers noticed that Maori living in coastal regions experienced fewer joint pains and arthritis than those living inland. The main difference between these groups was diet, and researchers homed in on raw green-lipped mussels as the most likely source of their joint health benefits. Green-lipped mussels benefits With the main function of green lipped mussels being joint inflammation reduction and maintenance, let’s discuss further the effect is has and how it functions: Green Lipped Mussel: main function The growing and harvesting process is all natural, sustainable and equally great for the environment. To be made into a supplement, the contents of the green lipped mussel is extracted, freeze dried, ground and put into a capsule. There are no toxins or chemicals consumed or added to the mussels before export.

Asthma patients can also benefit from taking green lipped mussel supplements. This chronic illness causes wheezing and shortness of breath due to inflammation of the lungs. It is an illness that has spiked in recent years and although prescription medication and equipment can help treat symptoms, ingredients found in those medications have been implemented into store purchasable supplements. Wang et al. [ 5] obtained similar results during the hydrolysis of M. edulis (blue mussel) using alcalase. They found that the antioxidant properties of blue mussel protein hydrolysates were greatly influenced by the time and enzyme used for hydrolysis. The radical scavenging effects of the peptides were lost during prolonged hydrolysis times due to the high degree of hydrolysis [ 7]. Working with the mussel variety Perna viridis (Asian green mussel), Ismail and Hasni [ 7] found that bioactive peptides with a high MW (>6 kDa) had stronger radical scavenging activity than low-MW peptides, and a high degree of hydrolysis resulted in the loss of antioxidant properties of the peptides. Working with yellow stripe trevally proteins using alcalase and flavorzyme, Klompong et al. [ 2] found that the antioxidant activity decreased with an increase in DH. Green Lipped Mussel is a type of shellfish and the largest type of mussel in the world. Known for its anti-inflammatory properties, it has grown in popularity as a natural supplement for the treatment of arthritis, particularly osteoarthritis, in both capsule and gel form. However, these findings can’t be attributed to the extract alone, as people in each of the studies were also taking pain-relieving medications. More than 27 million people in the USA are diagnosed and suffer with osteoarthritis every year. The risk of developing the condition increases with age, especially those over 60 years old.

Treatments for Your Dog

Green lipped mussel extracts have not been associated with any serious side effects, but obviously avoid green-lipped mussel extracts if you are allergic to shellfish. A variety of factors can contribute to arthritis in dogs: age, weight, breed, repetitive stress, bone fractures and dislocations, hip or elbow dysplasia, and joint surgery. Arthritis is commonly recognized and treated in our older canine pals, but often overlooked as it develops in young dogs, although it affects 20% of dogs over the age of one year, and 80% of dogs over the age of 8. Safety of GLMs

These oils are an extremely rich source of Omega 3 oils and serve as a powerful health supplement for treating inflammatory illness and joint pain. 5 Summary For example, early studies reported liver inflammation associated with a brand of supplements that contained toxins produced by the mussel ( 1). Not only do these nutrients and compounds help aid joint pain and inflammation, but they can also relieve muscular aches. Its high content of Glycosaminoglycans (GAG) provides vital support for muscle function and green lipped mussel gel delivers concentrated relief deep into the muscle tissue. Scientists have zeroed in on green-lipped mussels and tested their effectiveness and safety in relieving symptoms of osteoarthritis in humans and dogs. This is very important in the world of canine health because arthritis, also called degenerative joint disease, is the number one cause of chronic pain in dogs, according to the AKC Canine Health Foundation. More than one in five dogs will develop progressively worsening osteoarthritis, joint pain and dysfunction, with some beginning as young as one-year-old. Glycoproteins are proteins that have sugars attached to them. These sugars are the active component which works to reduce joint inflammation. They are also studied and proven to have benefits for the immune system as they increase response and reactiveness to reduce the effectiveness of bad bacteria and foreign invaders.

There are numerous medications in the pharmaceutical industry which can help treat it. However, the supplement market is now, more than ever, easier to access and rely on. One of the primary solutions for inflammation is omega-3 fatty acids, which is found in fatty fash. With that said, green lipped mussels can take a little longer to work in your dog compared to NSAIDs. But it’s worth the wait when you consider how much safer they are. From the results obtained, it was observed that the peptides present in the bioactive fraction obtained through RP-HPLC purification had numerous short peptides with MW < 5 kDa. Furthermore, in silico analysis (using the ExPASy tool) of the amino acid composition for these peptides suggested that there was an abundance of hydrophobic amino acids, such as Gly, Val, Lys, Ile, and Ala, in the peptide sequences compared to the presence of other polar and charged amino acids, which might have contributed to the high bioactivity observed [ 37]. The pepsin treatment of green-lipped mussels serves as a cheap and effective means of producing these bioactive peptides rather than synthetic adjuncts. Bioactive peptides with the strongest radical scavenging activity and ACE inhibitory activity would provide a promising solution for the control of cardiovascular diseases.