Lattoferrina 200 Immuno 30 Stick Pack PromoPharma

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Okada S, Tanaka K, Sato T, et al. Dose-response trial of lactoferrin in patients with chronic hepatitis C. Jpn J Cancer Res 2002;93:1063-9. View abstract. a b Giansanti F, Rossi P, Massucci MT, Botti D, Antonini G, Valenti P, Seganti L (2002). "Antiviral activity of ovotransferrin discloses an evolutionary strategy for the defensive activities of lactoferrin". Biochemistry and Cell Biology. 80 (1): 125–130. doi: 10.1139/o01-208. PMID 11908636. El-Hawy MA, Abd Al-Salam SA, Bahbah WA. Comparing oral iron bisglycinate chelate, lactoferrin, lactoferrin with iron and iron polymaltose complex in the treatment of children with iron deficiency anemia. Clin Nutr ESPEN 2021;46:367-371. View abstract.

Russo R, Superti F, Karadja E, De Seta F. Randomised clinical trial in women with recurrent vulvovaginal candidiasis: Efficacy of probiotics and lactoferrin as maintenance treatment. Mycoses. 2019 Apr;62(4):328-335. View abstract. Ohashi Y, Ishida R, Kojima T, Goto E, Matsumoto Y, Watanabe K, Ishida N, Nakata K, Takeuchi T, Tsubota K (August 2003). "Abnormal protein profiles in tears with dry eye syndrome". American Journal of Ophthalmology. 136 (2): 291–9. doi: 10.1016/S0002-9394(03)00203-4. PMID 12888052. Moskwa P, Lorentzen D, Excoffon KJ, Zabner J, McCray PB, Nauseef WM, Dupuy C, Bánfi B (January 2007). "A novel host defense system of airways is defective in cystic fibrosis". American Journal of Respiratory and Critical Care Medicine. 175 (2): 174–83. doi: 10.1164/rccm.200607-1029OC. PMC 2720149. PMID 17082494.Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine. Levin RE, Kalidas S, Gopinadhan P, Pometto A (2006). Food biotechnology. Boca Raton, FL: CRC/Taylor & Francis. p.1028. ISBN 978-0-8247-5329-0. Berthon BS, Williams LM, Williams EJ, Wood LG. Effect of Lactoferrin Supplementation on Inflammation, Immune Function, and Prevention of Respiratory Tract Infections in Humans: A Systematic Review and Meta-analysis. Adv Nutr 2022;13(5):1799-1819. View abstract. Das MR, Padhy LC, Koshy R, Sirsat SM, Rich MA (August 1976). "Human milk samples from different ethnic groups contain RNase that inhibits, and plasma membrane that stimulates, reverse transcription". Nature. 262 (5571): 802–5. Bibcode: 1976Natur.262..802D. doi: 10.1038/262802a0. PMID 60710. S2CID 4216981. van't Land B, van Beek NM, van den Berg JJ, M'Rabet L. Lactoferrin reduces methotrexate-induced small intestinal damage, possibly through inhibition of GLP-2-mediated epithelial cell proliferation. Dig Dis Sci 2004;49:425-33. . View abstract.

Lactoferrin ( LF), also known as lactotransferrin ( LTF), is a multifunctional protein of the transferrin family. Lactoferrin is a globular glycoprotein with a molecular mass of about 80 kDa that is widely represented in various secretory fluids, such as milk, saliva, tears, and nasal secretions. Lactoferrin is also present in secondary granules of PMNs and is secreted by some acinar cells. Lactoferrin can be purified from milk or produced recombinantly. Human colostrum ( "first milk") has the highest concentration, followed by human milk, then cow milk (150mg/L). [5] La frazione di questa proteina estratta dal latte contiene infatti il 3,3% di RNA, nonostante si leghi preferibilmente al DNA a doppio filamento piuttosto che al DNA a filamento singolo. Rosa L, Tripepi G, Naldi E, et al. Ambulatory COVID-19 Patients Treated with Lactoferrin as a Supplementary Antiviral Agent: A Preliminary Study. J Clin Med 2021;10(18):4276. View abstract.Miranda M, Saccone G, Ammendola A, et al. Vaginal lactoferrin in prevention of preterm birth in women with bacterial vaginosis. J Matern Fetal Neonatal Med. 2019 Nov 13:1-5. View abstract.

Kaufman DA, Berenz A, Itell HL, et al. Dose escalation study of bovine lactoferrin in preterm infants: Getting the dose right. Biochem Cell Biol. 2020 Aug 26. View abstract. Shongwe MS, Smith CA, Ainscough EW, Baker HM, Brodie AM, Baker EN (May 1992). "Anion binding by human lactoferrin: results from crystallographic and physicochemical studies". Biochemistry. 31 (18): 4451–8. doi: 10.1021/bi00133a010. PMID 1581301. Kuipers ME, de Vries HG, Eikelboom MC, Meijer DK, Swart PJ (November 1999). "Synergistic fungistatic effects of lactoferrin in combination with antifungal drugs against clinical Candida isolates". Antimicrobial Agents and Chemotherapy. 43 (11): 2635–41. doi: 10.1128/AAC.43.11.2635. PMC 89536. PMID 10543740. Due to Lf's critical and clear influence on many infections, the mechanisms behind this antiviral characteristic must be investigated in detail. The potential mechanisms that Lf might possess can point to evidence and explanation of Lf's prevention effect on SARS-CoV-2. In addition, Lf not only carries potential treatment agents against SARS-CoV-2 infection, but it also has a specialty in recovery with its influence on the overall immune system. In the future, Lf not only can be used as a therapeutic agent, but also can be used as a recovery supplement for patients infected with COVID-19. I recettori per la lattoferrina possono essere trovati sul tessuto intestinale, monociti / macrofagi, neutrofili, linfociti, piastrine e su alcuni batteri.Algahtani FD, Elabbasy MT, Samak MA, Adeboye AA, Yusuf RA, Ghoniem ME. The Prospect of Lactoferrin Use as Adjunctive Agent in Management of SARS-CoV-2 Patients: A Randomized Pilot Study. Medicina (Kaunas) 2021;57(8):842. View abstract. Ochoa TJ, Chea-Woo E, Baiocchi N, et al. Randomized double-blind controlled trial of bovine lactoferrin for prevention of diarrhea in children. J Pediatr. 2013;162(2):349-56. View abstract. According to an epidemiological update published by WHO in February 2022, globally there are 422 million cases followed with 5.8 million deaths ( 11). The current data shows even higher numbers with the updated version in near end of the August 2022, the COVID-19 pandemic that has extend to Europe (246,729,836), Americas (174,625,662), Western Pacific (81,762,210), South-East Asia (59,908,896), Eastern Mediterranean (22,946,608), and Africa (8,777,310), has still causing serious numbers of deaths ( 12). In England, between October 2020 and April 2021, people that got COVID-19 positive were classified according to their conditions; Individuals with conditions such as hypertension (15%), diabetes mellitus (8.6%), chronic respiratory disease (21.2%) at greater risk to exposed with coronavirus ( 12, 13). The genetic and physical structure of SARS-CoV-2

Rosa L, Tripepi G, Naldi E, Aimati M, Santangeli S, Venditto F, etal. (September 2021). "Ambulatory COVID-19 Patients Treated with Lactoferrin as a Supplementary Antiviral Agent: A Preliminary Study". Journal of Clinical Medicine. 10 (18): 4276. doi: 10.3390/jcm10184276. PMC 8469309. PMID 34575388. Ali AS, Hasan SS, Kow CS, Merchant HA. Lactoferrin reduces the risk of respiratory tract infections: A meta-analysis of randomized controlled trials. Clin Nutr ESPEN 2021;45:26-32. View abstract. Troost FJ, Saris WH, Brummer RJ. Recombinant human lactoferrin ingestion attenuates indomethacin-induced enteropathy in vivo in healthy volunteers. Eur J Clin Nutr 2003;57:1579-85. View abstract.The moonlighting glycolytic enzyme glyceraldehyde-3-phosphate dehydrogenase ( GAPDH) has been demonstrated to function as a receptor for lactoferrin. [35] Bone activity [ edit ] a b Farnaud S, Evans RW (November 2003). "Lactoferrin--a multifunctional protein with antimicrobial properties". Molecular Immunology. 40 (7): 395–405. doi: 10.1016/S0161-5890(03)00152-4. PMID 14568385.