Cabergoline for men & women: Dostinex (Know Your Medicine)

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Once your prolactin levels are within a normal range, you’ll be expected to begin to ovulate and then menstruate again. You can then try to conceive naturally, unless you need help with another type of fertility problem. If that’s the case, you may need to try assisted-conception treatments. Cabergoline is a very effective treatment for hyperprolactinemia (Molitch 2015, NCCWCH 2013). It’s growing in popularity as a fertility treatment as it has a better success rate than bromocriptine and fewer side effects (Molitch 2015). NCCWCH. 2013. Fertility: assessment and treatment for people with fertility problems. National Collaborating Centre for Women's and Children's Health, NICE Clinical Guideline. www.nice.org.uk Opens a new window [Accessed October 2016]

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If you take too much: You could have dangerous levels of the drug in your body. Symptoms of an overdose of this drug can include: If you miss doses or don’t take the drug on schedule: Your medication may not work as well or may stop working completely. For this drug to work well, a certain amount needs to be in your body at all times. Cushing syndrome is characterized by unusually high levels of cortisol, usually caused by chronic oral steroid use. Treatment depends on the… READ MORE You may also be prescribed dopamine agonists if you’re having IVF and you’re at risk of ovarian hyper-stimulation syndrome (OHSS) (HFEA 2015). Cabergoline is currently recommended for this as it is an effective treatment that won't affect your chance of pregnancy or increase your risk of multiple pregnancy (NICE 2015). How long will fertility treatment with dopamine agonists last?Your exact dosage will depend on your particular fertility problem and which drug you’ve been prescribed. You’ll be under the care of a specialist doctor, who may increase your dose slowly whether you are taking cabergoline or bromocriptine (BNF 2016).There are other drugs available to treat your condition. Some may be better suited for you than others. Talk to your doctor about other drug options that may work for you.

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Disclaimer: Healthline has made every effort to make certain that all information is factually correct, comprehensive, and up-to-date. However, this article should not be used as a substitute for the knowledge and expertise of a licensed healthcare professional. You should always consult your doctor or other healthcare professional before taking any medication. The drug information contained herein is subject to change and is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. The absence of warnings or other information for a given drug does not indicate that the drug or drug combination is safe, effective, or appropriate for all patients or all specific uses. Dosage increases: Your doctor may increase your dosage by 0.25 mg. This decision depends on your prolactin levels. Your doctor may increase your dosage once every 4 weeks. It’s considered safe to take dopamine agonists for long periods, even for several years (Melmed et al 2011, Hartree 2012). Do dopamine agonists have any side-effects?Common side-effects of bromocriptine and cabergoline include: Always use Caberlin (Cabergoline) as you have been prescribed by your doctor. Never self-medicate or change your dosage without first consulting your doctor. The correct dosage can vary depending on your health, medical history, and the severity of the condition being treated.Fertility drugs are prescribed medications that will mostly help to influence the ovulation process. It can either help to start the ovulation process or help to strengthen the ovulation cycle to release at least one or more eggs within the cycle. Fertility drugs are the most commonly used treatment for couples who are facing infertility issues. The most common cause of infertility within women are ovulation difficulties. Hormones like estrogen and testosterone are crucial to your health, and a hormonal imbalance can cause symptoms like acne and weight gain. Learn more. READ MORE A systematic review and meta-analysis concluded that prophylactic treatment with Cabergoline reduces the incidence of ovarian hyperstimulation syndrome (OHSS). Usually this is prescribed within your IVF treatment. Cabergoline is currently recommended for this as it is an effective treatment that will not affect your chance of becoming pregnant or increase your risk of multiple pregnancies. Cabergoline is used to treat hyperprolactinemia (high levels of prolactin in your body). This happens when your pituitary gland makes extra prolactin. High prolactin levels may be caused by a hormone problem or by a tumor in your pituitary gland.

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Express Delivery (Please be aware when you select Courier Next Day for northern parts of Scotland, DPD may take 2 days to deliver) Hartree N. 2012. Hyperprolactinaemia and prolactinoma. www.patient.co.uk Opens a new window [Accessed October 2016] Cabergoline is commonly sold under the name Dostinex. Because certain steroids can raise prolactin levels, a lot of people who are sensitive to prolactin can run the risk of gynecomastia. Running Cabergoline prevents this from occurring. It’s also popular to use because it will fight off erectile dysfunction and a decreased libido. Before taking Caberlin (Cabergoline) tablets, a medical consultation will be necessary, to allow your doctor to prescribe the correct dosage for you. Adults treating hyperprolactinemia may be prescribed an initial dose of 0.25mg taken by mouth, twice per week. The prescribing doctor may decide to increase this by 0.25mg taken twice a week. The maximum dosage is usually 1mg taken twice per week. It is important for patients to note that the dosage prescribed can depend on the patient`s serum prolactin levels, and for this reason, it is very important to follow the prescribing doctor`s instructions.Cabergoline oral tablet can cause drowsiness as well as other side effects. More common side effects

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For people with liver problems: You may not be able to process this drug well. This may increase the levels of the drug in your body and cause more side effects. Warnings for other groups As cabergoline suppresses milk production, you should not take it whilst breast feeding. It is often helpful to see whether your periods start again when you have stopped breast feeding, and reassess your prolactin levels, before deciding whether or not to resume cabergoline treatment. Sometimes microprolactinomas resolve after a pregnancy. Rarely, women with large macroprolactinomas will be advised to continue cabergoline treatment and not to breast feed. Your endocrinologist will discuss these decisions with you. Are there any medicines I should avoid when taking cabergoline? HFEA. 2015. Getting started: your guide to fertility treatment. Human Fertilisation & Embryology Authority. www.hfea.gov.uk Opens a new window [Accessed October 2016]When your baby breastfeeds, or you pump your breast milk, the nerves in your breasts send a signal to your brain to release the hormones; oxytocin and prolactin. The prolactin tells the milk glands in your breasts to make more breast milk, and the oxytocin is responsible for getting the breast milk from your breasts to your baby. This is why it can be dangerous to still consume Cabergoline when you fall pregnant, as if you do not have that high level spike of prolactin within the body, you may not start to produce any breast milk. Allen H. 2014b. Cabergoline tablets (Dostinex, Cabaser). patient.info Opens a new window [Accessed October 2016] Cabergoline is a long-acting medication, usually taken once or twice a week. Cabergoline can make you feel a bit dizzy, or cause nausea or headaches. Side-effects may be reduced if you take the cabergoline with food, or last thing at night before going to bed. Usually your specialist will recommend a low starting dose to reduce the risk of side-effects, gradually increasing the dose if necessary as your body gets used to the medication. Rare side-effects of cabergoline